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Abstract

A REVIEW ARTICLE ON PRONIOSOMES

V. Sarovar Reddy, Deepa Mopuri*, P. Neelaphar and P. Alekhya

ABSTRACT

In recent times, no single drug delivery system fulfills all the criteria, but attempts have been made through novel approaches. Many novel approaches emerged covering various routes of administration, to achieve either controlled or targeted delivery. The prime aim of novel drug delivery is maintenance of the constant and effective drug level in the body and minimizing the side-effects and it also localizes the drug action by targeting the drug delivery by using drug carriers. Vesicular drug delivery is one of the approaches, which encapsulate the drug e.g.: Liposomes, niosomes, transferosomes, pharmacosomes, and provesicles such as proniosomes and proliposomes. Advantages of liposomes and niosomes over other conventional dosage forms are their particulate nature, which act as a drug reservoir. Few modifications can also be carried out in order to adjust the pattern and the drug release. It was also found out that modified vesicles had properties that successfully delivered drugs into deeper layers of the skin.

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