ANTIMICROBIAL APPLICATION OF SCHIFF’S BASE AND IT’S METAL COMPLEXES: A REVIEW
R. G. Mahale* and Deepak V. Nagarale
ABSTRACT
In last decades Aliphatic, Aromatic and heterocyclic compounds
containing one or two heteroatoms are gain attention of researchers
knowing importance of Schiff’s base and its application in
pharmaceuticals and drug manufacturing as well as in the synthetic
compounds of biological interest.[1] Here we reviewed some synthetic
methods, Schiff’s base and its complexes formed from condensation of
the carbonyls and amines keeping its application regarding biological
activity in global prospective. Schiff bases are a popular class of
compounds with interesting biological properties. Schiff bases are also
versatile metal complexing ligands and have been used to coordinate
almost all d-block metals as well as lanthanides and found various
application were patented its therapy of Schiff bases.[2]
Keywords: Antimicrobial Activity, Schiff’s Base, Metal Complex, Inorganic preparations, Pharmaceutical.
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