PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF MEDHYA RASAYANA TABLET- A COMPOUND AYURVEDIC FORMULATION
Monika Solanki*, K. S. Patel, V. K. Kori, Harisha C. R. and Shukla V. J.
ABSTRACT
Behavioral problem in young children is Very common. Enuresis is
defined as the voluntary or involuntary repeated discharge of urine into
clothes or bed. This problem greatly affects psychosocial life of child
as well as family members. It affects small to middle age group of
children mainly. It is considered as multifactorial behavioral disorder.1
In Ayurvedic classics, the brief description regarding Shayyamutra is
found in Sharangadhara2 and Vangasena Samhita3. This disease
mainly involved Vata (Apan Vayu), Pitta (Pachaka), Kapha (Tarpaka),
along with Manasika Dosha Tama. There are many treatment option
are now available for disease but traditionally very less information was available for the
same. Medhya Rasayana is compound of Ayurvedic formulation mentioned in Charak
Samhita text for the treatment of various psychiatry illnesses4. Medhya Rasayana contais
Brahmi, Shankhapushpi, Yastimadhu, Guduchi. The present study was carried out to
standardize the finished product Medhya rasayana to confirm its identity, purity and quality.
The presence of Epidermal cells, Colonchyma cells, Starch grains, Covering trichoma,
Crystal fibers, Pitted vessels, Rhomboidal crystals, Cork cell etc were the characteristic
features of observed in microscopy of drug. Physico chemical analysis shows loss on drying
is 4.88% w/w, water soluble extract is 13.9% w/w, methanol soluble extract is 9.48% w/w,
ash value is 5.20% w/w and PH is 6.0. High Performance Thin Layer Chromatography
(HPTLC) at 254 nm and 366 nm resulted into 8 & 7 spots respectively.
Keywords: Medhya Rasayana, Shayyamutra, Pharmacognosy, Pharmaceutics, HPTLC.
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