WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

SYNTHESIS, GREEN METRICS EVALUATION AND ANTIBACTERIAL ACTIVITY OF 3,4,5-TRIMETHOXY–N- [SUBSTITUTED (ARYL/HETEROARYL) METHYLENE)BENZENAMINE DERIVATIVES

Shalini, Birendra Kumar*, Binita Kumari and B. Ram

ABSTRACT

Schiff bases, such as nitrofurantoin or nifuroxazide, are commonly applied in medicine as antibacterial agents. They are well known for their biological application as antibacterial, antifungal, antiviral, anti- HIV, anti-protozoal, anti-cancer agents. The present paper describes the synthesis of Schiff‟s base 3,4,5-trimethoxy-N- [substituted(Aryl/Hetero-Aryl)methylene)benzenamine derivatives 5am from commercially available gallic acid. These derivatives were synthesized by condensation with 3,4,5-trimethoxyanline using various aromatic and hetero-aromatic aldehydes in presence of ZnO Nano particles at room temperature. Furthermore, the present paper describes the green metrics evaluation data for the synthesized Schiff‟s base derivatives (5a-m) and its associated intermediates. In addition to the above, these compounds were screened for their antibacterial activity.

Keywords: Schiff?s base, Gallic acid, 3,4,5-Trimethoxy aniline, Synthesis, Green metrics


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More