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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
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Abstract

REVIEW ON PHOTOSTABILITY STUDIES OF FORMULATION

Mulchand A. Shende* and Rajendra P. Marathe

ABSTRACT

This article tries to provide a fabulous journey of various studies that have been takes place in photostability evaluation and development of photostable formulations. This article includes photodegradation process, factors affecting process, various ways to tackle with photostability problem and regulatory aspects for photostability studies. The ways which are being used to tackle photostability problem include light resistant container, antioxidants, light absorber or pigments, light resistant coating, inclusion complexation with cyclodextrins, liposomes, microspheres, microcapsules and ionexchange resins. The recent works show that the ion-exchange resins and complexation with cyclodextrins are being effective and can be used commercially for manufacturing of photostable formulations of photosensitive drugs.

Keywords: Photostability, Inclusion complexation, Ion-exchange resins.


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