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Abstract

STUDY OF THE PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF CASSIA AURICULATA

M. Prem Nawaz, V. Ramamurthy* and S. Rajamohamed

ABSTRACT

Medicinal plants form the backbone of traditional system of medicine in India. Pharmacological studies have acknowledged the value of medicinal plants as potential source of bioactive compounds. Ethanolic extracts of Cassia auriculata were used traditionally in India for the treatment of skin diseases. The present study was investigated for invitro antimicrobial activity against pathogens namely Staphylococcus aureus, Bacillus subtilis, Streptococcus pyogenes, Pseudomonas auroginosa, Klebsiella pnemonia, Aspergillus nĂ­ger, Trichoderma viride and Candida albicans using the agar well diffusion method. The results relevant that the plant leaf extract possessed the highest inhibitory activity against the bacteria (Staphylococcus aureus in 23 mm) and fungi (Candida albicans in 14 mm). Among the leaf extracts of C. auriculata possess the highest inhibitory activity then the root extracts. In parallel study was performed to identify the distribution and the concentration of the phytocompounds in the roots and leaves of this plant. For this purpose we have prepared alcoholic extracts from each part of the plant and we have studied them separately.

Keywords: Antimicrobial activity, Cassia auriculata, Phytochemical analysis.


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