WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NOVEL CHALCONE DERIVATIVE

Ashish Kaushik* and Manoj Kumar Prabhakar

ABSTRACT

Chalcones are 1,3-diphenyl-2-propene-1-one, in which two aromatic rings are linked by a three carbon α, β- unsaturated carbonyl orgenic compound and report to possess a wide spectrum of biological activity such as antibacterial, antifungal, anticancer, antioxident e.t.c. the biological activity of chalcon derivative is due to enonepharmacophor in their structure. These are abundant in edible plants and are considered to be precursors of flavonoids and isoflavonoids. In an effort to develop antimicrobial agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate. Acetophenones with aromatic Aldehydes in the presence of aqueous solution of potassium hydroxide and ethanol at room temperature. Benzaldehyde and an Acetophenone in the presence of sodium hydroxide as a catalyst, chalcones can also be prepared by an aldol condensation. the structure of this compound is well supported by U.V, NMR, IR, MASS Spectral data. the compound has been evaluated for their antimicrobial activities.

Keywords: antimicrobial, chalcone, synthesis.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More