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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
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Abstract

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 6-ARYL-4- METHYL-2-THIO-1, 2, 3, 6-TETRAHYDROPYRIMIDINE-5-(N-ARYL) CARBOXAMIDES: A STRUCTURE-REACTIVITY STUDY

S. Manimekalai, K. Radhakrishnan* and S. Chandra Mohan

ABSTRACT

A novel series of Biginelli type dihydropyrimidinones derivatives were synthesized and investigated for their antibacterial activity against Gram positive and Gram negative bacteria. The recorded data of zone of inhibition showed significant broad activity when compared with standard. The structure reactivity correlation of the compounds has been studied.

Keywords: Biginelli type compounds, dihydropyrimidinones derivatives, antibacterial activity, correlation studies.


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