Abstract

PHARMACEUTICAL STANDARIZATION OF GANDHAKAKALPA

Dr. G. Madhubabu* and Dr. G. Rameshbabu

ABSTRACT

Gandhakakalpa (GK) is a Rasoushadhi mentioned in Basavarajeeyam indicated for all types of Kushta (obstinate skin diseases including Eczema). Gandhaka (Sulphur), Triphala (Homogenous mixture of Haritaki, Vibitaki, Amalaki), Trikatu (homogenous mixtureof Shunti, Pippali, Maricha), Vidanga (Embeliaribes) and Chitrakamula (Plumbagoxylanica) are the main ingredients of GK. Shodhana (purification), Choornodaka Nirmana, Choorna Nirmana arethe important steps involved in preparation of GK. shuddha Gandhaka & shuddha Chitramula were taken. The remaining herbal churnas were added in appropriate amount as mentioned in reference of the drug. After obtaining homogenous mixture. It was made 500mg tablets. Till date no standards are available for the above drug. Therefore the present study has been planned to standardize the method of preparation of an important Herbo-mineral formulation i.e. Gandhakakalpa.

Keywords: Gandhakakalpa, Rasoushadhi, Basavarajeeyam, Kushta.