WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

EVALUATION ANTIBACTERIAL EFFECTS OF GARCINIA KOLA AND VERNONIA AMYGDALINA ON STAPHYLOCOCCUS AUREUS ISOLATED FROM RESIDENTS OF ABUJA. NIGERIA

Opara John-Kennedy I., Onwuliri F. C., Agumah N. B.*, Njoku O. M., Onwuliri E. A.

ABSTRACT

This study was carried out to ascertain the antibacterial effects of extracts of Garcinia Kola and Vernonia amygdalina on Staphylococcus isolated from residents of Abuja. Fresh Bitter Kola seeds and Vernonia amygdalina leaves were purchased from various markets in Abuja. Some of them were collected from domestic gardens. Extracts were prepared and tested upon isolates of Staphylococcus aureus obtained from various clinical smaples. The crude extract of Bitter Cola showed activity against S. aureus, with mean zones of inhibition (ZOI) of 6.36 ±0.36 mm (3.9 ±0.6 - 8.9±0.6); compared to mean ZOI of 5.96 ±0.62 mm (5.2 ±0.3 - 6.7±0.8) recorded in Bitter Leaf. Aqueous extracts of Bitter Cola exhibited higher antimicrobial activities, ZOI: 8.66 ±0.42mm (5.3 ±0.4 - 13.5 ±0.4), compared to mean ZOI of 5.96±0.62mm (5.2 ±0.3 - 6.7±0.8) recorded in V. amygdalina. On the other hand, aqueous extracts of Bitter Cola exhibited higher antimicrobial activities with a ZOI of 8.66 0.42 mm (5.3 ±0.4 - 13.5 ±0.4) compared to 6.36 ±0.36 mm (3.9 ±0.06 - 8.9 ±06 mm). Both crude and aqueous extracts of test plants exhibited significant (P<0.05) effects against S. aureus. The inhibitory activities of G. kola and V. amygdalina did not differ significantly (p> 0.05). The MIC of Garcinia kola seed extract ranged from 0.045–0.049 mg/mL. While the MBC of the extract ranged from 0.1268–1.25mg/mL. Similarly, the MIC of Vernonia ranged from 0.0016–0.1486 mg/mL and the MBC ranged from 0.0611–2.45 mg/mL respectively. The MBC values were much higher than the MIC values. Thus, is suggestive of bacteriostatic action of Garcinia and Vernonia extracts on S. aureus.

Keywords: Abuja, Staphylococcus, Vernonia, Garcinia, Antibacterial.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More