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Abstract

DIFFERENT TECHNIQUES FOR PREPARATION OF NANOEMULSION WITH CHARACTERISATION AND VARIOUS APPLICATION OF IT - A REVIEW

Gharge Varsha Gajanan*, Gore Meghana Milind and Dr. Yadav Adhikrao

ABSTRACT

Nanoemulsion are the most of the rapidly developing field of nanotechnology with several applications in drug delivery, medical and research as that of other medical sciences and develop new therapeutics. Nanoemulsions are clear, thermodynamically stable, isotropic liquid mixtures of oil, water, surfactant and co-surfactant. These are oil-in-water (o/w) type of emulsions with the average droplet size ranging from 5nm to 100 nm. Reduction in droplet size to nanoscale leads to change in physical properties such as optical transparency & unusual elastic behavior. Nanoemulsions/ Sub-micron emulsions (SMEs)/ Mini-emulsions are thermodynamically stable transparent or translucent dispersions of oil and water stabilized by an interfacial film of surfactant and co surfactant molecules having a droplet size of less than 100 nm. The present review gives highlight on the different techniques for preparation and characterization of Nanoemulsions as particle size, zeta potential, stability study and the importance of Nanoemulsions in pharmaceutical applications.

Keywords: Nanoemulsion, nanotechnology, surfactant and co surfactant, techniques for preparation, pharmaceutical applications.


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