Abstract

ANTIMICROBIAL ANALYSIS OF POLYHERBAL FORMULATION LINKUS COUGH SYRUP

Hina Rehman, Khizra Jamil, Aymen Owais, Safila Naveed and Khan Usmanghani

ABSTRACT

The Herbal products has widely use throughout the globe since 5,000 years. The objective of this study is to determine the antimicrobial analysis of Polyherbal formulation Linkus cough syrup and its comparison with the other antibiotics recommended. Linkus syrup tested for anti-microbial activity against Staphlococcous Aureus, Streptococcous pyogenes, Salmonella and Pseudomonas Aeruginosa. Mc Farland principles were adopted for maintaining the turbidity in bacterial microorganism. TSA is recommended for clinical laboratories for susceptibility testing procedures and maintenance of microbial culture. Antimicrobial testing were performed on agar and well diffusion method. For agar disc diffusion method, the disc were 0.7 cm and well was prepared with the help of a cork-borer were 0.85 cm. The results of the study showed that the linkus cough shows strong sensitivity against Staphylococcus Aureus, Streptococcus pyogenes and Salmonella in both disc and well diffusion method and showed resistivity against Pseudomonas Aeruginosa. However with the comparison of amoxicillin and ampicillin, linkus showed more sensitivity against Salmonella and Streptococcus pyogenes. The poly herbal blend of Linkus syrup can be used as an anti-microbial agent on cough and associated symptoms related to upper respiratory tract infections.

Keywords: Antimicrobial analysis, polyherbal formulation.