ANTIMICROBIAL ANALYSIS OF POLYHERBAL FORMULATION LINKUS COUGH SYRUP
Hina Rehman, Khizra Jamil, Aymen Owais, Safila Naveed and Khan Usmanghani
ABSTRACT
The Herbal products has widely use throughout the globe since 5,000
years. The objective of this study is to determine the antimicrobial
analysis of Polyherbal formulation Linkus cough syrup and its
comparison with the other antibiotics recommended. Linkus syrup
tested for anti-microbial activity against Staphlococcous Aureus,
Streptococcous pyogenes, Salmonella and Pseudomonas Aeruginosa.
Mc Farland principles were adopted for maintaining the turbidity in
bacterial microorganism. TSA is recommended for clinical laboratories
for susceptibility testing procedures and maintenance of microbial
culture. Antimicrobial testing were performed on agar and well
diffusion method. For agar disc diffusion method, the disc were 0.7 cm
and well was prepared with the help of a cork-borer were 0.85 cm. The results of the study
showed that the linkus cough shows strong sensitivity against Staphylococcus Aureus,
Streptococcus pyogenes and Salmonella in both disc and well diffusion method and showed
resistivity against Pseudomonas Aeruginosa. However with the comparison of amoxicillin
and ampicillin, linkus showed more sensitivity against Salmonella and Streptococcus
pyogenes. The poly herbal blend of Linkus syrup can be used as an anti-microbial agent on
cough and associated symptoms related to upper respiratory tract infections.
Keywords: Antimicrobial analysis, polyherbal formulation.
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