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Abstract

A REVIEW ON RECENT ADVANCES IN ENTERIC COATING AND ENTERIC POLYMERS

P. Mounica*, S. Pavani and P. Mounica Rani

ABSTRACT

Worldwide many researchers are seeking the knowledge or the advances of the enteric coating and the role of polymers. The present review focuses on the elevation of enteric coating and polymers. Enteric coated means a tablet or capsule or the other form of oral medication which is layered with a defensive coating. This coating is used to fortify the stomach from unwanted effects or detrimental effects of a medication. It is most frequently used in aspirin and other NSAIDs that are known to antagonize the stomach lining, but is also often used in medications or vitamins that need to dissolve in the small intestine and absorb properly. The main important role of enteric coating is to release the drugs after the stomach. The word enteric actually mean referring to the intestine. Most of the polymers are either man made or natural and they won’t break down below levels of pH 5.5. From a pharmacological point of view the term enteric coating is not entirely scrupulous, because the gastric resistance can also be obtained by adding enteric polymeric systems. So in order to obtain a gastro resistant drug it should have enteric coating and suitable polymers for the dosage form. Different polymers were used in enteric coating like cellulose acetate phthalate, polyvinyl acetate phthalate, hydroxyl propyl methyl cellulose. The enteric coating was done on different type of dosage forms like tablets, capsules, pellets and granules. Recently there are so many advancements in the enteric coating.

Keywords: Enteric coating, systemic absorption, enteric coating polymers, intestine.


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