WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

UV-SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF ROSIGLITAZONE MALEATE IN PHARMACEUTICAL DOSAGE FORMS

Snigdharani Behera*, Sujit Kumar Martha and Pratit Kanchan Sahu

ABSTRACT

The objective of the proposed method is to develop simple & accurate method for the determination of Rosiglitazone maleate by UV spectrophotometric method in pharmaceutical dosage forms. Stock solution of Rosiglitazone was prepared & the calibration curve was drawn by suitable dilution of the standard solution. Commercially available Rosiglitazone tablet was taken & analysed. And the validation of the adopted method was ascertained by Precision & Accuracy. From the studies, it was found that, Rosiglitazone obeys linearity within the concentration range of 1-80μg/ml. From the results of precision study, it was found that the % R.S.D is less than 2%, which indicates that the method has good reproducibility. From the results of accuracy study, it was found that the % recovery values of pure drug from the pre-analysed solution of formulation were in between 97.5-98.12%, which indicates that the proposed method is accurate. The proposed method is specific while estimating the commercial formulations without interference of excipients and other additives.

Keywords: Rosiglitazone, Methanol, Precision, Accuracy, Validation.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More