WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

ANTIARTHRITIC ACTIVITY OF ETHANOLIC EXTRACT OF FICUS RELIGIOSA LEAVES IN FCA INDUCED ARTHRITIS IN RATS

Vivek D. Rathod*, Digambar N. Ware, Shibu Pillai, Jitendra O. Bhangale and Pradnya J. Bhangale

ABSTRACT

The present study was carried out to evaluate the antiarthritic activity of ethanolic extract of Ficus religiosa leaves on FCA induced arthritis in rats. The crude ethanolic extract was administered orally at a dose 100, 200 and 400 mg/kg, body weight from day 13 to day 21. Arthritis was assessed by various parameters such as body weight, arthritic score, paw volume and ankle diameter on day 0, 3, 6, 9, 12, 15, 18 and 21. At the end of study, animals were anesthetised and blood was collected for the estimation of various haematological parameters such as haemoglobin content, total RBA, WBC, ESR count, CRP level and TNF alpha level. The result indicated that at a dose of 200 and 400 mg/kg b.w., EtFR protect the rats against primary and secondary lesions, body weight, paw swelling and haematological perturbations induced by FCA. There was a significant increase in body weight, reduction in arthritic score, paw volume and ankle diameter in extract treated animals. Above findings were confirmed by haematological results as, significant improvement in the levels of Hb and RBC count, and suppressed WBC count, ESR count, CRP and TNF alpha levels found in EtFR administered arthritic group. Our finding showed a significant antiarthritic activity of Ficus religiosa leaves against FCA induced arthritis in rats.

Keywords: Ficus religiosa, Rheumatoid arthritis, FCA.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More