SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 2-{1’-ARYL-1’- [4’’-(2’’’-HYDROXY ETHOXY ETHYL) PIPERAZIN-YL]-METHYL}- CYCLOHEXANONE HYDROCHLORIDE
Rakesh P. N. Roshan, D. M. Purohit and Sandip K. Matariya*
ABSTRACT
2-{1’-Aryl-1’-[4’’-(2’’-hydroxyethoxy ethyl)piperazin-yl]-methyl}-
cyclohexanone hydrochloride (4a-4l) have been synthesized. The
products have been assayed for their antimicrobial activity against
Gram+ve, Gram-ve bacteria and fungi. All the products were assigned
with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some
of the products showed moderate activity, compare with known
standard drugs.
Keywords: 2-{1’-Aryl-1’-[4’’-(2’’-hydroxyethoxy ethyl)piperazin-yl]-methyl}-cyclohexanone drugs.
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