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Abstract

COMPARATIVE STUDY ON THE SPERMICIDAL ACTIVITY OF DATURA METAL AND ALLAMANDA CATHARTICA FLOWER EXTRACTS

Dr. S. Anu Kiruthika and Dr. R. Sornaraj

ABSTRACT

A comparative study was planned to investigate the spermicidal activity of the extracts of Datura metal and Allamanda cathartica flowers. The Datura metel extract was identified as the best one and hence it was used for further indepth spermicidal activity. The extract was administered to Rates at different doses and the reproductive activity of the rat was assessed. The extract showed remarkable alterations on the morphology and physiology of the sperm cells. There was a notable reduction in the sperm count, reduction in the size of testes, epididymis and production of testosterone.

Keywords: Datura metal, Allamanda cathartica, Epididymes, Spermicidal, Seminal vesicle.


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