WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF PERGULARIA DAEMIA (FORSK) CHIOV, AGAINST MULTIDRUG RESISTANCE HUMAN PATHOGENIC BACTERIA

Madhuri M. Deshmukh* and Navnath G. Kashid

ABSTRACT

The increasing number of multidrug resistant bacteria to conventional antibiotics has become a serious problem in recent years. So there is alarming need to investigate new antibiotics and alternative products to solve this problem. This research aim is to search potent herbal drugs from Pergularia daemia extracted in different solvent system considering their polarity and non polarity nature. Pergularia daemia stem part extracted in different solvents, Methanol, Ethanol, Chloroform, Petroleum Ether, Ethyl Acetate and Aqueous solution. The technique used for extraction is of Soxhlet Apparatus and Rotary evaporator. Effective extracts obtain tested against some pathogenic bacteria, Escherichia coli, (ATCC-25922), staphylococcus aureus (25923ATCC) Klebsiella pneumonia, Salmonella typhi (734 MTCC). Among all tested extracts aqueous extract proved most powerful antibacterial activity compare to standard antibiotics amoxicillin for these bacteria, aqueous followed by ethyl acetate. Methanol and Ethanol extract showed less antibacterial effect. Chloroform and Petroleum Ether extract does not showed any activity. Antibacterial activity of solvent extracts was tested by Disc Diffusion and Agar Well Diffusion method. This research also highlights on the existing information particularly on the phytochemistry alkaloid, phenolic compound, steroids, flavonoids, which may provide incentive for proper evaluation of the plant as a medicinal agent.

Keywords: Pergularia daemia, Antimicrobial activity, Human Pathogen, E.coli, S. aureus, Kleb. Pneumoniae, S. typhi. secondary metabolites.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More