ANTIBACTERIAL SCREENING OF ANDROGRAPHIS ECHIOIDES (L.) NEES AGAINST SELECTED HUMAN PATHOGENIC BACTERIA
Dr. T. Francis Xavier and D. Sathish Kumar*
ABSTRACT
Andrographis echioides (L.) Nees is a valuable medicinal plant. The
present study is to investigate the antibacterial activity of the various
leaves and stem extracts of A. echioides. Shade dried plant leaf and
stem of A. echioides were tested for antibacterial the antibacterial
activity of different extracts (petroleum ether, chloroform, acetone,
methanol and ethanol) of leaves and stem of A. echioides using the
standard disc diffusion assay against four gram-positive bacterial
species, viz., Staphylococcus haemolyticus, Staphylococcus lentus,
Staphylococcus aureus and Bacillus cereus six gram-negative bacterial
species viz., Escherichia coli, Serratia marcescens, Enterobacter
amnigenus, Klebsiella pneumonia, Klebsiella oxytoca and Brevibacterium paucivorans.
Among various solvent extracts studied acetone, methanol and ethanol leaf and stem extract
showed a highest antibacterial assay followed by chloroform and petroleum ether. No results
found in petroleum ether leaf and stem extract against all test bacteria. Hence the present
study justifies the claimed uses of this herb in the traditional system of medication to treat
various sicknesses. This report is an antibacterial screening from A. echioides leaf and stem.
Keywords: Andrographis echioides, Antibacterial, Disc diffusion method.
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