WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Venkateswaran Chidambaram Seshadri*, Packiaraj Jeyachandran Manohari,
Janakiraman Kunchithapatham and Jayanarayan Kulathingal


Glaucoma is a progressive, neurodegenerative optic nerve disease that can cause significant visual morbidity and affects over 60 million people worldwide. The latest marketed product in the form of ophthalmic solution to treat the glaucoma is RESCULA® with a novel prostaglandin analogue, Unoprostone Isopropyl as active ingredient at 0.15% w/v. Characterization by laser diffraction of the marketed product revealed the drug product in the nano emulsion form. The API, Unoprostone Isopropyl is a clear colorless viscous oily liquid, practically insoluble in water and poorly permeable. The formulation utilized 1% Polysorbate 80 as solubilizer; 0.05% Disodium Edetate as preservative, chelating agent and antioxidant; 0.015% Benzalkonium Chloride as preservative; 4.3% Mannitol as osmotic agent; Sodium Hydroxide / Hydrochloric Acid at quantity sufficient for pH adjustment. The final product was sterilized through filtration using polyvinylidine filters. The filtrate was packed in Low Density polyethylene bottle with dropper insert capped with High Density Polyethylene closure. The stability of the product was evaluated and found to be stable in both upright and horizontal position at ICH recommended accelerated stability condition of 40ᵒC / 25% RH.

Keywords: Sonication, Sterile filtration, Stability.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More