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Abstract

SUB ACUTE TOXICITY STUDY OF Daikon (VEGETABLE) EXTRACT ON ALBINO RATS

Baranidharan B.* and Shamina S.

ABSTRACT

The present study was to evaluate phytochemical composition and effect of various concentration of methanolic extract of Daikon (vegetable) on haematolgical parameters in male albino rats. The phytochemical screening were done with methanol, ethanol, chloroform, petroleum ether and water. The result showed the presence of alkaloids, flavonoids, tannins, steroids, terpenoids, and glycosides. The best results were found in methanolic extract, hence it is used for further study. In toxicity studies they were given 150,250,350,450,550mg/kg doses of the methanolic extract for 90 days. The rats were sacrificed and the blood was collected by cardiac puncture then used for haematolgical and biochemical parameters. Results from the present study have elucidated that there was no significant signs of toxicity at any dose level used in the study. Physical, biochemical as well as hematological parameters was unaltered throughout the study.

Keywords: Haematological and biochemical parameters, Daikon, phytochemical screening.


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