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Abstract

NERVE GROWTH FACTOR: AN IMPORTANT TARGET FOR NEUROPROTECTION

Darshana Patil*, Neha Jadhav and Rachana Sarawade

ABSTRACT

Protection of neurons i.e. Neuroprotection is the only and important way to stop neurodegeneration. Neurodegeneration is slowly, progressive and irreversible mechanism if remained untreated. Now-adays there are many strategies are present to overcome with the problem of neurodegeneration. Nerve growth factor is one of the important factor to target neuroprotection. Nerve growth factor is neurotrophin which helps neurons for their survival and differentitaion. NGF,BDNF,GDNF,NT-3,NT-4 seems to play crucial role in diseases like Parkinson’s and Hypoxic ischemic brain injury. Therefore in this review, wesummarize recent literature focusing on neuroprotection through various nerve growth factor.

Keywords: Neurodegeration, Neuroprotection, Prakinsons Disease, HIBI, NGF, GDNF.


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