WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Dr. Archana Joshi*, Dr. Leena Gajare and Dr. Sadhana Mahore


The nephrotic syndrome (NS) is a clinical syndrome complex characterized by number of renal and extra renal features and is defined by a urinary protein level exceeding 3.5 gm per 1.73 m2 of body-surface area per day. The aim was to study clinical profile, the histopathological spectrum of renal biopsies in NS and to correlate histopathological spectrum with clinical profile. Material and methods: Total 120 patients of all age groups diagnosed clinically with NS and subjected to renal biopsy were included in study while those with insufficient biopsy material were excluded from our study. Results: In the present study patient’s age ranged from 6 to 79 years with the mean age of 36.73 + 15.81 years. Male: Female ratio was 2:1. Overall most common etiology of NS was Minimal change disease (MCD) and in pediatric age group was Focal and segmental glomerulosclerosis (FSGS). Most common cause of primary NS was MCD while Diabetic nephropathy (DN) was most common cause of secondary NS. Most common clinical presentation was pedal edema. Elevated serum creatinine was observed in 21 patients. Hypercholesterolemia was detected in 89 patients. Microscopic hematuria was present in 47 patients. The most common complication in our NS study was urinary tract infection (UTI) followed by acute kidney injury (AKI), chronic kidney disease (CKD), pneumonia and thrombosis. All patients had hypoalbuminemia. All patients were seronegative for HIV, HBsAg and HCV. All 6 patients with LN had ANA and dsDNA positive. Conclusion: MCD is the most common cause of NS in adults while FSGS in pediatric age group. In view of changing histological spectrum of NS it is essential to maintain a national renal biopsy registry data which would help to obtain accurate knowledge of spectrum, presentation, incidence and complications.

Keywords: Nephrotic syndrome, renal biopsy, spectrum of renal disease.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More