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Abstract

MICROEMULSION: A NOVEL APPROACH FOR IMPROVED DRUG DELIVERY

Ahmad Bala Musa Kazaure*, Deepa Mohan Singh and Himanshu Amarchand Chawla

ABSTRACT

Microemulsion are liquid dosage form which is biphasic in nature; they include the combination of oil and water as one formulation with the help of surfactants (Polyoxyethylene/Polysorbate/Tween 20,40,60,80) and co-surfactants (Ethanol, propanol, Isopropanol, butanol), which act as surface acting agent whereby reducing the surface tension between the two component (water and oil). Such agents form a clear, isotropic and thermodynamically stable with the same physical properties in all directions. As the name suggests microemulsion is emulsions having a less particle size compared to the normal emulsion formulations, the particle size ranges from (10-100nm) which are far more less than an emulsion particle size of (1-10mm). A microemulsion is potential drug carrier for the various route of administration which includes: topical, nasal ophthalmic, drug targeting, cellular, brain, and other different drug delivery systems, where it has an advantage compared to other dosage forms by its ability to improve bioavailability, promotes taste masking and also absorption rate. In order to fully understand the full concept of the microemulsion, this article explains briefly the major key regarding microemulsion and the main basic idea behind it with reference to the scientific facts.

Keywords: microemulsion, biphasic, isotropic, clear, particle size.


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