WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

SYNTHESIS AND INITIAL ANTICANCER ACTIVITY OF WATER AND DIMETHYL SULFOXIDE SOLUBLE POLYETHERS FROM ZIRCONOCENE DICHLORIDE AND POLY (ETHYLENE GLYCOLS)

Charles E. Carraher Jr.*, Michael R. Roner, Jessica Frank, Kendra Black, Alisa Moric-Johnson, Lindsey C. Miller, Francesca Mosca and Paul Slawek

ABSTRACT

The initial synthesis of DMSO and water-soluble zirconocene polyethers through the reaction of zirconocene dichloride and various poly(ethylene glycols) employing commercially available reactants is described. Infrared, proton NMR, and MALDI MS results are consistent with the zirconocene-containing polyether structure. The materials are polymeric, with chain lengths ranging from 4700 to 5 with moderate product yield. They exhibit good inhibition of a variety of cancer cell lines including two pancreatic cancer cell lines.

Keywords: metal containing polymers, PEG polymers, zirconocene-containing polymers, cancer, pancreatic cancer, water soluble polymers, MALDI MS.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More