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Ibrahim Mohamed Saeed Shnawa*


The immune molecules (Complement, interferons), the immune receptors (TLRs,KIR,KAR,CD38), the functioning immune cells(Neutrophil, eosinophil, dendritic, langrhans, T and B cells) and glands (Salivary and Tonsils) are coexisted in the oral cavity. These elements(Except the glands) may be of local, systemic or both of local and systemic origins. Such components are the formed elements of the oral mucosal immune compartment. In this mini-review, an expression was made about each of their elements for; the structure, general function, systemic immune cross – road function and a deduction on the possible oral immune cross- road function. The immune cross-road functions means the mono or bidirectional cooperation between the natural(Innate) and adaptive immunity. There were an evident analogy between the systemic immune cross-road functions with the possible oral immune cross-road functions. Such analogy have led to the opinion holds the position that there was a real oral immune cross-road functions covering; immune proteins, immune receptor and immune cells constitute a tripartite system. Thus, oral immune compartment is a mini-ature of the tripartite systemic immune system.

Keywords: Cross-road, function, immune, molecule, receptor, structure.

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