WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Das S, Sehgal VK, Vardhan A


Fungi are non-motile eukaryotic cells, which cannot photosynthesise and many are parasitic in nature. Although many are economically important, edible, useful in production, about 50% are pathogenic to human beings. Human fungal infections have increased dramatically in incidence and severity in recent years. The recent advances in surgery, cancer treatment, HIV, increased use of antimicrobials have left patients vulnerable for these infections. Nowadays, Invasive fungal infections, specially by Aspergillus and Mucorales are causing morbidity and mortality in patients of organ transplantation and stem cell transplantation. Several new antifungal drugs have been launched recently, but still there is difficulty to treat which may be due to antifungal resistance, certain organs like eye show poor penetration of these drugs, whereas treatment is futher hampered due to appearance of severe adverse effects. Isovuconazonium (Cresemba, Astellas Pharma Inc), a broad spectrum triazole agent, which is administered as a water soluble prodrug, has been approved by the U.S. Food and Drug Administration and the European Medicines Agency for treating adults suffering from invasive aspergillosis mucormycosis. This drug has also shown actions against other species like Candida alongwith better tolerability. Phase 3 trials show Isovuconazonium to be a possible option among current therapies.

Keywords: Isovuconazonium, invasive fungal infections, Aspergillosis.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More