Abstract

SCREENING OF ANTI BACTERIAL AND ANTI FUNGAL ACTIVITY OF GANDHAKA DRUTI

*Dr. B. Saravanan, M.D (AYU)

Abstract

Antimicrobial agents are commonly used nowadays for treating various bacterial and fungal infections. But still most of the physicians are unable to treat these infections appropriately due to hindrances like development of resistance, adverse effects, patient affordability etc. Gandhaka druti formulation mentioned in Ayurvedic Texts can be an ideal replacement for treating various infectious diseases. Assessment of its antibacterial and antifungal activity may provide scientific evidence for the study. Gandhaka druti prepared with classical reference was subjected for antibacterial and antifungal activity by cup plate method. The drug was tested against bacteria like Staphylococcus aureus, Pseudomonas auregenosa and E coli and fungi Aspergillus niger, Cryptococcus neoformans, Candida albicans and Trycophytum rubrum taking Fluconazole as standard for comparison. Gandhaka druti showed a significant zone of inhibition against three strains of bacteria and four strains of fungi when compared to Fluconazole standard. Gandhaka druti showed a significant antibacterial and antifungal activity. Antibacterial activity was significant compared to antifungal activity.

Keywords: Gandhaka druti, Antimicrobial agents, Flucanozole.