Abstract

COMPARATIVE EVALUATION OF POVIDONE IODINE AND ALOE VERA ON GINGIVAL HEALTH: A RANDOMIZED CONTROLLED TRIAL

*Dr. Sana Ambereen, Dr. Harsha Mysore Babu, Dr. Vivekananda M. R., Dr. Shivaprasad D. and Dr. S. Ravindra

Abstract

Background: Mechanical therapy has been strengthened by adjunctive use of several anti-plaque agents in the effective treatment of plaque induced gingivitis. Aloe vera, an herbal product, known for its antibacterial and anti-inflammatory property, has been shown to significantly reduce gingival inflammation. Povidone-iodine has broad spectrum antimicrobial effect against harmful periodontal pathogens. This study aimed to compare and evaluate the efficacy of Aloe vera and Povidone iodine as an antimicrobial and anti-inflammatory mouthwash in plaque induced gingivitis. Materials and methods: The study was conducted for 30 days on 45 subjects. The patients were randomized into three groups namely Aloe vera (Group A), Povidone iodine (Group B) and Chlorhexidine group (Group C). Clinical parameters like Plaque index (PI), Gingival index (GI), Sulcus Bleeding Index (SBI) and microbiological parameter like Gram’s staining for quantitative assessment of Gram positive and Gram negative organisms and immunological parameter IL-6 Level were assessed at baseline and at the end of 1 month. Results: The results of the current study showed that the mean scores of PI, GI, SBI and microbial count and the levels of IL-6 at one month had decreased to lower values in the three groups which were statistically significant. Conclusion: 99% Aloe vera mouthwash was as effective as 0.2% chlorhexidine and had better efficacy then 1% Povidone iodine mouthwash in treating chronic generalized gingivitis.

Keywords: Aloe vera, Povidone iodine, Gingivitis, Chlorhexidine Gluconate, Interleukin-6.