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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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ICV : 90.8

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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.

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Abstract

NANOCOCHLEATE â€“ AN IMPORTANT DRUG DELIVERY SYSTEM OFFERING UNIQUE FEATURES

*Sangita Fulchand Pawar, Sunil S. Bothara, Paresh R. Mahaparale and Vikram L. Musale

Abstract

There are various lipid-based nanocarriers systems are available in current scenario. Among these lipid-based nanocarriers multi-layered cochleates emerge as a novel nanocarrier system for hydrophilic and hydrophobic drugs with better and improved stability, efficacy, improved drug permeability and reduction in drug dose. It also helps to increase oral bioavailability of hydrophilic and hydrophobic drugs and helps for site specific drug delivery with less side effects. This article focuses on structure and composition of cochleates, various method of preparation of cochleates, mechanism of drug delivery, applications, evaluation and limitations of nano cochleates.

Keywords: Liposomes,Lipid-based nanocarrier, Nanocochleate.

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