Abstract

A PILOT STUDY TO EVALUATE IMPROVEMENT IN LOWER URINARY TRACT SYMPTOMS WITH TAMSULOSIN AND DUTASTERIDE COMBINATION THERAPY IN PATIENTS WITH BENINGN PROSTATIC HYPERPLASIA AND TO EVALUATE THE IMPACT OF PATIENT COUNSELLING ON QUALITY OF LIFE OF PATENTS

Devika V. S., Krishna Mol J., Sakkeena A., Abhiram R. Sajeev, E. Samjeeva Kumar*, Prasobh G. R.

Abstract

Objective: To evaluate improvement in lower urinary tract symptoms with tamsulosin and dutasteride combination therapy in patients with beningn prostatic hyperplasia and to evaluate the impact of patient counselling on quality of life of patients. Patients and methods: 15 patients were included in the study and were given tamsulosin and dutasteride combination therapy (0.4+0.5)mg OD. Patients were interviewed during firdt visit in the department appropriate patient counselling was provided and were followed up in the next two weeks. The patients improvement in lower urinary tract symptoms and satisfaction on treatment was assessed by using IPSS Score(International prostate symptom score) questionarre and the impact of patient counselling on quality of life was assessed by using IPSS Q8 and BPH impact index(BII)at each visit. Results: A total of 15 patients with BPH along with Lower urinary tract symptoms fulfilled the study criteria were included. Improvement in LUTS by using Tamsulosin + Dutasteride combination therapy were assessed with IPSS scores. Most of them have improvement in their voiding symptoms than storage symptoms by using combination theraphy. Medication adherence were also assessed in these patients. Conclusion: From this study it is concluded that most of samples showed improvement in LUTS using Tamsulosin + Dutasteride combination therapy. Pharmacist intervention in the form of counselling is hence an integral factor in improving the quality of life in patients and also medication adherence of patients.

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