Abstract

ANALYSIS AND DETECTION OF EFFECT OF LEAD AND ALCOHOL ON VITAMIN C OF BRAIN TISSUE OF RATS

Anusuya M.R.*

Department of Biochemistry, Kempegowda Institute of Medical Sciences, Bangalore, India.

Abstract

In vitro evaluation of effect of lead and alcohol on vitamin C content on brain tissue was evaluated at four and eight weeks of duration in brain tissue of rats. In four hours of treatment, The vitamin C content ranged from 393.0 g/gram in the cerebral cortex of control rats. The lead treatment was characterized by a decrease in vitamin C content 336.5g/gram. In alcohol treated rats, the decrease in vitamin C content 233.0g/gram were higher compared to lead treated rats. In eight hours of treatment, the brain tissue of rats recorded the vitamin C content was 315.0 g/gram in the cerebral cortex of control rats. The lead treatment was characterized by a marginal decrease in vitamin C content 284.0g/gram In alcohol treated rats, the decrease in vitamin C content 256.0 g/gram. The vitamin C content were decreased in rats coexposed to alcohol and lead, and recorded 205 g/gram.

Keywords: Vitamin C, Lead, Alcohol, Vitamin E, Brain tissue, Rats.