Abstract

ANALYSIS OF CHEMICAL-QUANTUM INTERACTIONS BETWEEN QUERCETIN, SARS-COV-2 PROTEINS, AND COVID-19

Manuel González-Pérez*, Juan Carlos Colín-Ortega, Elvira Elizabeth Cortes-Aguirre, Donovan González-Martínez and Eva Luz González-Martínez

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Abstract

Flavonoids or phenolic acids are antioxidants present in plants. Quercetin (QCT) is a carbohydrate-free flavonoid, very abundant in vegetables and fruits. This compound has a wide range of antioxidant, anti-inflammatory, and immune-regulating effects and cardiac and neurological protection. The objective of this article was to analyze the chemical-quantum interactions between quercetin and the spike proteins of the sars-cov-2 causing covid-19. Hyperchem software was used to carry out all simulations. The ETC theory was used to calculate this coefficient to rank the interactions. As a result, the oxide-reduction interactions of QCT vs. AAs from sars-cov-2 proteins. Sixty-one interactions were made. The predominant oxidation interactions in quartile I am 15 and 6 in quartile II. There are no predominant reduction interactions in quartile I. There are only five predominant reduction interactions in quartile II. In total, 26 interactions can inactivate or destroy sars-cov-2 proteins. As a general conclusion, we have found that QCT can neutralize or even destroy sars-cov-2 and, at the same time, strengthen the human immune system.

Keywords: Quantum chemistry, Quercetin, Proteins, Amino acids, Sars-Cov-2, Covid- 19.