Abstract

SAFETY, EFFICACY AND MANAGEMENT OF ASTHMA WITH ICS/LABA THERAPY: A REVIEW

Kavya Catherin*, Jelany K. Raju, Lal Jose E., Happy Thomas and Rosmin Jacob

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Abstract

Asthma is a chronic inflammatory condition of the airways. Management of asthma with Inhaled Corticosteroids (ICS) and Long acting β2 agonist (LABA) in patients with persistent symptoms or uncontrolled asthma with a low to moderate dose of ICS alone, improves asthma control, decrease the exacerbation and future risks. Commonly prescribed ICS/LABA therapy includes, Salmeterol/ Fluticasone, Fluticasone/ Formoterol, Budesonide/ Formoterol. Various studies conducted have demonstrated the efficacy and potency of different ICS/LABA combination therapy. However, the uses of these medications have raised safety concern also. The purpose of this review is to establish the safety, efficacy and management of ICS/ LABA therapy from various reviews and studies conducted.

Keywords: Asthma, ICS, LABA, safety, efficacy, treatment, SABA, side effects.