Abstract

EFFECTS OF ANTIVIRALS, GLUCOCORTICOIDS AND VARIOUS SUPPLEMENTS IN MANAGEMENT OF COVID-19

Sameer S.*, Dr. Prasobh G. R. and Dr. Julia J. J.

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Abstract

The COVID-19 infection pandemic has resulted in significantly raised economic and public health issues. Moreover, there is an associate degree pressing out to discover effective medication, prevention and control methods due to the high death toll of this new corona virus infection. Acute respiratory tract infections that mainly include lower respiratory tract infections and pneumonia are the leading cause of millions of deaths worldwide. The role of micronutrients, together with trace components, in stimulating the human immune system has been well established. Numerous vitamins like vitamin C, D, folate and microelements which includes zinc, plays essential physiological roles in promoting the immune system. It also helps regulate gene transcription, such as DNA replication, RNA transcription, cell division and cell activation in the human biological system. Methods: Previously published articles regarding Covid-19. Observations: Remdesivir (Antiviral) is a broad spectrum antiviral agent that has previously demonstrated antiviral activity against SARS-CoV-2 in vitro. Glucocorticoids can be useful in prevent cytokine-induced alveolar / pulmonary damage and chemokine storm. Zinc plays essential physiological roles in promoting the immune system, an indispensable microelement essential for a complete physiological enzymatic process. Vitamin D, another fat-soluble vitamin, plays a vital role in modulating both innate and adaptive immune responses. Vitamin C is known as an antioxidant and essential enzyme cofactor for many physiological reactions in the body, such as hormone production, collagen synthesis and immune boosting.

Keywords: Covid -19, Antivirals, Glucocorticoids, Zinc, Vitamin D, Vitamin C.