Abstract

A REVIEW OF FLUCONAZOLE LOADED TRANSETHOSOMAL GEL FOR CANDIDIASIS

Shilpa Shyam M.* and Shammika P.

.

Abstract

Candidiasis is one of the most common fungal infections. For the treatment, antifungal therapy is used. Fluconazole is considered as most effective as compared to other antifungal drugs. Various disadvantages occur when the drug is administered as conventional form. In this review dealing with the latest form of vesicular system like transethosome. When the drug is incorporated in the form of transethosome which nullify the all the disadvantages when it is formulated in any other conventional systems and there by provide stable and more effective formulation, and also having high patient compliance. Transethosome containing high concentration of ethanol along with edge activator which provide high penetration to the skin and leads to better therapeutic action.

Keywords: Candidiasis, Transethosomal gel, antifungal, bioavailability, chitin, Edge activator.