Abstract

KSHETRA DUSHTI IN POLYCYSTIC OVARIAN SYNDROME: AN OBSERVATIONAL STUDY

*Dr. Nidhi Bajpai, Dr. Anuradha Roy and Dr. Binay Sen

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Abstract

Background: Polycystic ovarian syndrome (PCOS) affects 6-18% of women with metabolic, inflammatory, and endocrine abnormalities on ovulatory function, oocyte quality, and endometrial receptivity. Even when ovulation is restored, there is altered cellular endometrium affecting the endometrial receptivity at the time of implantation which is likely to be associated with subfertility and increased miscarriage rates. Recent studies have also showed increased risks of pregnancyinduced hypertension, preeclampsia, and premature delivery that may be related to altered decidualization/placentation in PCOS affected women. endometrial factor (kshetra) comes under the four essential factors for conception i.e. ritu, kshetra, ambu, beeja. Endometrium plays a major role in proper conception and obstetrical outcomes. Objective: Here we aimed to examined endometrial receptivity status in patients of PCOS and to assess the association between PCOS and endometrial defects. Design and method: The present study was set in the department of Prasuti tantra, IMS BHU. Participants were women diagnosed with PCOS and healthy females of reproductive age group. Criteria for assessment was USSR (Uterine scoring system of reproduction) score of uterine biophysical profile which was done on 22nd to 24th day of LMP. Conclusion: The study shows that PCOS patients had endometrial defects also with ovulatory defects. Here we conclude that there must be prior consideration to nurture and correct kshetra (endometrial factor) before the patient with PCOS get conceived either by assisted reproductive techniques or natural methods to improve the obstetrical outcomes.

Keywords: Endometrial receptivity, Uterine biophysical profile, Kshetra dushti.