Abstract

COMPARATIVE ASSESSMENT OF GENERIC AND BRANDED MEDICINE IN SOLID DOSAGE FORM

Aishwarya A. Yadav*, Sonali Sidharam Savalgi, Ashwini Badardinni, Samiksha Neungare, Ajay Kumar Yadav and Dr. Nagesh C.

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Abstract

The main objective of the proposed work was comparative assessment for generic and branded medicine. Generic medications offers substantial potential cost saving to health systems compared to their branded counterparts. The present study was aimed to evaluate and compare the quality of generic medicine (Losartan potassium tablet) with their branded (LOSAKIND-50) counterparts as per Indian Pharmacopeial (IP) standards and other validated methods. Generic drugs are as effective as their branded counterparts in terms of safety and efficacy. The selected generic and branded tables are coded as G1, G2, G3 and B1, B2, B3 respectively. Each tablet were evaluated for the official test like drug content, weight variation, thickness, friability, disintegration, dissolution, drug release kinetics. Non official test includes hardness test. The study revealed that branded as well as generic tablets comply with the standards provided in IP. From the results based on the evaluation parameters of tablets and in-vitro dissolution rate studies, the generic Medicines showed similar results as branded. And had identical quality and they fulfilled all the criteria prescribed by the IP. This confirms that the generic medications are of equivalent and comparable quality of the branded medicine available in the market.

Keywords: generics, branded medicine, Losartan potassium, Jan Aushadhi.