Abstract

IN VITRO ANTIDIABETIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF HELIOTROPIUM INDICUM BY ALPHA AMYLASE ENZYME INHIBITION METHOD

*Kathiravan M., Prathap B., Mohamed Halith S., Saran Kumar R., Sameeha Banu B.,  Selvamani S., Sathishkumar P. and Senthamilvalavan P.

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Abstract

Medicinal Plants play a key role cure many diseases from immemorial. The usage of plants in traditional medicinal system is the vital process of india.[1] Diabetes mellitus (DM) is a group of metabolic disorders characterized by a chronic hyperglycemic condition resulting from defects in insulin secretion, insulin action or both. According to a report from World Health Organization, about 220 million people have type 2 DM. Its incidence is increasing rapidly, and it is expected to increase to more than 365 million by 2030. From this work carried out by the in-vitro antidiabetic activity of ethanolic leaf extract of Heliotropium indicum and Acarbose act as standard by inhibition of Alpha amylase enzyme method. It has promoting antidiabetic activity by inhibition of Alpha amylase enzyme method. It has to be further evaluvated to produce a safe herbal formulation for the treatment of diabetes mellitus.

Keywords: Diabetes mellitus, Ethanolic extract, Anti-diabetic activity, Heliotropium indicum.