Abstract

A CASE REPORT ON CRYPTOCOCCAL MENINGITIS

Mohammed Abrar, Nawaz Khan K. R. and Dr. Savanthi Chitrahasini*

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Abstract

Cryptococcal Meningitis is an infectious disease of worldwide distribution caused by the fungus Cryptococcus neoformans. The fungus primarily attacks the lungs, causing torulomas, but produces few or no symptoms referable to lungs. Cryptococcal meningitis has become the leading cause of morbidity and mortality from infection in AIDS patients. Approximately 1 million cases of cryptococcal meningitis are reported each year. A 40-year-old female patient was admitted with chief complaints of fever for 15 days which is on and off type associated with headache for 15 days associated with blurring of vision, 10 episodes of vomiting in the past 1 day bilious in nature. Her history says she has been IDV-positive for 2 years on medication. The patients CSF analysis shows the presence of cryptococci microorganism. And CT shows DNS towards the right side &Mucosal thickening in the bilateral maxillary sinus. The patient was given Inj.Dexamethasone, Inj.Cefotaxime, Inj.Liposomal Amphotericin B, Tab.Fluconazole, Tab.Nitrofurantoin, Syp.Sucralfate, Inj.Metoclopramide, Syp.Potasium chloride, Tab.Cotrimoxazole. As there was a Adverse drug reaction of Amphotericin B induced hypokalemia, Further Investigations are necessary to avoid Drug interactions or ADRs due to ART & treatment of Meningitis.

Keywords: Meningitis, HIV, Opportunistic infections, CT brain, CSF Analysis.