Abstract

A REVIEW ON IMPORTANCE OF NOVEL DRUG DOSAGE FORMS IN AYURVEDA W.S.R TO MODERN DOSAGE FORMS

*Dr. Madduru Muni Haritha, Dr. Prashant G. Jadar and Dr. U. B. Bolmal

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Abstract

Ayurveda being ancient science, acharyas mentioned chikitsa chatushpadas like bhishak, Dravya, rogi, upastha. Where Dravya was given 2nd prime importance in treatment of diseases. In Ayurveda, there is description of panchavidha Kashaya Kalpana namely swarasa, kalka, kwatha, hima, phanta and their upakalpanas intended to use both externally and internally for therapeutic benefit, but these kalpanas cannot be used as such, as they need to undergo few modifications. In present sophisticated society demand for finished products lead to adaption of newer modern and ayurvedic pharmaceutical technology in manufacturing of ayurvedic formulations to meet the trends of present society. Importance to develop new dosage forms was given in such a way that the new dosage form is designed considering compatibility palatability, easily availability, easy administration, smaller dose, convenient method of usage and enhanced bioavailability to the patient. It is also used to increase the shelf life of the particular preparation. These kalpanas explained in the classics are modified making it, compactable without losing the efficacy of a drug, considering ideal drug qualities mentioned by charaka which also involves yukti of the physician to modify the medicine while considering principles of samyaga, vibhaga, kala, samskara with respective to desha, kala, bala etc. In this view as per need, ayurvedic drugs are modified into convenient forms like tablets, capsules, dispersable tablets, suspensions, capsules, dusting powders, gels, creams, liniment, sprays, transdermal patches, granules, syrups, Nano form of medicine etc, based on solids, liquid and semisolid forms.

Keywords: Novel dosage form, Panchavidha kashaya Kalpana, Ayurvedic pharmaceutics, saviryata avadhi, shelf life.