Abstract

DRUG DISCOVERY AND DEVELOPMENT

Pooja M. Sontakke*, Suraj G. Malpani, Pooja R. Tange, Sampada S. Kolhe, Mayuri J. Chandrawanshi and Vishweshwar M. Dharashive

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Abstract

The process of drug discovery aims to find a compound that can be used to treat and cure diseases. It involves identifying potential candidates, synthesizing, characterizing, validating, optimizing, and screening them for therapeutic efficacy. Once a promising compound is identified, it goes through a rigorous drug development process that includes clinical trials and regulatory approvals to ensure it is safe and effective. This process is lengthy, complex, and expensive, requiring the consideration of multiple biological targets for every new medicine. New research tools may be necessary to investigate these targets. It takes around 12-15 years and a billion dollars to develop a marketable medicine. On average, only one out of a million screened molecules makes it to late-stage clinical trials and is made available to patients. This article provides an overview of the drug discovery and development process.

Keywords: Drug Discovery, Validation, Optimization, Screening, Clinical Trials etc.