Abstract

PHARMACEUTICAL PREPARATION AND PHYSIO- CHEMICAL ANALYSIS OF AMRITA GUGGULU PREPARED WITH OR WITHOUT MURCHHIT GHRUTA

Sanjiv Kumar* and Prabhat Kumar Dwivedi

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Abstract

Ayurvedic medicines are prepared in rasa shastra as rasausadhi and bhaishajya Kalpana. It is essential to maintain the analytical standards of each sample for better therapeutic effect. Amrita guggulu of Chakradutta Vatarakta Chikitshaprakaram reference is one such herbal formulation that contain a major proportion of shhoddhita guggulu and other ingredients of Triphala, Trikatu, Danti, Vyosha, Vidang, Triphala, Tvak (Dalchini) and Trivrit and Guduchi. In this preparation two samples taken one is without Ghruta murchhana levigation and other with bhavana i.e., Ghruta Murchhana. Ghruta Murcchana is a unique pharmaceutical process prior to the preparation of Amrita guggulu formulations. The present study was focused on analytical studies of without murchhita goGhruta bhavana and Murcchita Go-Ghruta bhavana which was carried out separately on the basis of classically illustrated organoleptic tests, modern physio-chemical parameters like Loss on Drying at 110°C, Acid Value, Alcohol soluble value, water soluble extractive, total bacterial count, total fungal count, disintegration time in N/10 Hcl, In N.S. in different parameters sample which has bhavana of Murchhit Go-Ghruta has more therapeutic than sample I. Hence the present work may be used for the quality assessment and standardization of Amrita guggulu.

Keywords: Amrita guggulu, murchhit go-Ghruta, pharmaceutical preparation, physio-chemical analysis.