Abstract

AN OVERVIEW OF WET GRANULATION TECHNIQUE FOR BULK DRUG TABLET FORULATION

*Virendra Chika Pawara and Vaishali T. Khairnar

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Abstract

The wet granulation method is simple, precise, accurate, and selective for the estimation of drugs in bulk and is in tablet dosage forms, the method is economical, rapid and do not require any sophisticated instruments. This review also describes about the techniques used for preparation of wet granulation and also describes about stages of granules development. A judicial selection of appropriate technology for carrying out the granulation processes the key to achieve a targeted granulation and final product parameters. in depth knowledge of the processing techniques and their merits and demerits is required to adopt during development stage of product.

Keywords: Wet Granulation, Binder Solution, Nucleation, Coalescence, Granules.