Abstract

PREVALENCE OF EPSTEIN- BARR VIRUS IN CERVICAL CARCINOMA

Rushdi S. Fadhil*

Abstract

The human herpes virus Epstein-Barr (EBV) is clearly associated with African Burkitt's lymphoma and the undifferentiated form of nasopharyngeal carcinoma, although its role in oncogenesis is still poorly defined. Recently EBV has been implicated in other types of lymphomas, as well as in some non lymphomatous neoplastic processes. It's possible association with human cervical carcinoma has been investigated here .The present study included (40) patients having cervical carcinoma with age ranged (40–70) years, where histopathological sections reviewed .A second group regarded as control group complained of healthy women , (40) women with age ranged (40 -70) years. ELISA technique had been used to detect about IGg of VC Ag and E Ag of EBV. We identified that EBV- lgG were non-significant (p >0.05) in compared with control group . The non-significant association between EBV and cervical carcinoma that we have found further strengthens the suggestion that cases of cervical carcinoma should be increase and assessed for EBV status by PCR technique because its more specific and more sensitive test than ELISA technique.

Keywords: EBV, ElISA, virus , cervical carcinoma.