Abstract

IN VITRO MEMBRANE STABILIZING ACTIVITY OF LEAF EXTRACTS OF PAEDERIA FOETIDA (L.)

Mohammad Shahriar*, Md. Tanveer Ahsan, Sultana Mehbuba Hossain, Sayeeda Fahmee Chowdhury, Mohammad Mooneem Mannan, Rumana Akhter, Sadia Mahmud, Sabbir Hasan and Syeda Najah Narjish

Abstract

In this present study, the leaf extracts of Paederia foetida were subjected to evaluation of the membrane stabilizing activity by using human erythrocyte and the results were compared with standard antiinflammatory drug, acetyl salicylic acid (ASA). In vitro membrane stabilizing activity for hypotonic solution induced haemolysis, the ethanol extract inhibited 76.92% haemolysis of RBCs as compared to 85.42% produced by acetyl salicylic acid (ASA) and during heat induced condition different organic soluble materials of Paederia foetida demonstrated 76.68%, 77.19% and 74.83% inhibition of haemolysis of RBCs respectively whereas ASA inhibited 78.04%.

Keywords: Paederia foetida, membrane stabilizing activity, human erythrocyte, acetyl salicylic acid.