Abstract

DETECTION OF HELICOBACTER PYLORI IN ATHEROMA OF ISCHAEMIC HEART DISEASES PATIENTS IN THE SOUTH OF IRAQ BY PCR TECHNIQUE

Awatif H.Issa (Prof. Ph.D)*, Manal B. Salih (Assent. Prof.Ph.D), Saffaa S. Omran (MSc.), Nezar H,Issa (Phys. Ph.D)

Abstract

Ischaemic heart disease (IHD) or coronary heart disease (CHD), It is the end result of the accumulation of atheromatous plaques within the walls of arteries that supply the myocardium; Recent study confirmed identification of H. pylori deoxyribonucleic acid (DNA) in atherosclerotic plaques of patients with severe coronary artery disease, which supports the hypothesis that H. pylori infection may influence the development of atherosclerosis. The study aimed to detect presence of H. pylori DNA in the atheroma or intima of 50 subjects (which were divided into two sub groups: persons with IHD and persons without IHD) by PCR technique, the study showed that 3% of persons with IHD and 6% of persons without IHD had positive results and 4% (from all subjects) of study, without regard to group type, had positive results.

Keywords: Pylori deoxyribonucleic,