Abstract

MICROWAVE IRRADIATED SYNTHESIS, SPECTRAL, ANTIBACTERIAL AND ANTIFUNGAL CHARACTERIZATION OF Zn(II) and Cd(II) COMPLEXES WITH 2,4-THIAZOLIDINEDIONE AND BENZOATE ION

L.Palanivelan*, S. Balasubramaniyan, K. Rajasekar, R. Govindharaju and T. Ramachandramoorthy

Abstract

Transition metal complexes of Zn(II) and Cd(II) with 2,4- thiazolidinedione (TZD)and benzoate ion(BEN) have been synthesized under microwave irradiation and characterized by elemental analysis, metal estimation, molar conductance, UV-Visible, IR, Far-IR and NMR spectral studies. Composition and non-electrolytic nature (1:0 type) of the complexes were confirmed by the elemental analysis, metal estimation and molar conductance values. The probable geometry of the complexes was arrived from the UV spectral data. IR and Far-IR spectra of the complexes confirmed the TZD coordination through nitrogen atom whereas benzoate ion can coordinate through the oxygen atom. The NMR spectra of the complexes are confirmed the entry of the ligand into the coordination sphere of the metal ions. The antibacterial and antifungal activities of various microorganisms viz., Chromo Burcol, salmonella, S.aures, seratia, C.albicans, Aspergilus were studied at various concentrations (30 & 50 ml) by disc diffusion method. All the complexes show the higher activity than the free ligand.

Keywords: 2,4-thiazolidinedione, Benzoate ion, Metal complexes Microwave, Microorganisms.