Abstract

SYNBIOTICS: A COMPREHENSIVE REVIEW ON THEIR COMPOSITION, MECHANISMS, AND THERAPEUTIC POTENTIAL IN DISEASE MANAGEMENT

Yash Bilaye*, Pooja Kumbhar, Gauri Vahalkar

Abstract

Synbiotics combine probiotics consist of live beneficial microorganisms and prebiotics, non- digestible substrates that selectively enhance probiotic survival and activity. So when probiotics and prebiotics are put together as synbiotics, they attempt to ensure that your gut has a good proportion of living microorganisms more than when using probiotics and prebiotics together. However, synbiotics may act in different ways depending on how they act when mixed together. In some ways, they act as complements where each component does the exact same thing. Other times they act as synergists where the prebiotic is utilized by probiotics; as a result, you become even healthier. This is because, as stated above, the prebiotic is used specifically by probiotics to ensure that good things happen. A ―synbiotic,‖ assists in improving the health status of your gut by using probiotics and prebiotics together. This article gives an entire description of synbiotic compounds and explains the appropriate strains and substances that should be used as well as the major processes that occur when using synbiotics. There are several processes through which synbiotics work effectively. The increasing demand for syn- biotics can be identified from a few recent researches that reveal the potentiality of synbiotics in the management and treatment of various ailments such as insulin resistance, obesity, irritable bowel syndrome, and colon cancer. When the use of synbiotics or both probiotics and prebiotics are taken individually, a few benefits stand out in synbiotics such as their viability, activity, and efficacy rate.

Keywords: Synbiotics, Probiotics, Prebiotics, Gut health, Therapeutic Applications.