Abstract

A DETAILED REVIEW ON FAST DISSOLVING ORAL FILM

*Wasim J. Bagwan, *Ravi U. Kurhade, *Akshata T. Budde, Madhushri Chavan, Rajnandani Kamble, Umme Sheiza Bagwan

Abstract

The oral route of drug administration is one of the most preferred routes of drug administration because of its low cost and ease of administration increases patient compliance. Fastdissolving drug delivery systems (FDDDS) were developed for those patients who have difficulty swallowing tablets and hard gelatine capsules especially geriatric and pediatric patients. This dosage form is an alternative to tablets, capsules, and syrups. Fast-dissolving oral thin film is a more acceptable and accurate oral dosage form that bypasses hepatic first-pass metabolism and provides a therapeutic response by increasing bioavailability. This technology has been used for local action and rapid release of the drug. It is relatively a new dosage form in which thin film is prepared using hydrophilic polymers, which rapidly disintegrate or dissolve on the tongue or in the oral cavity. The present review gives an account of different formulations, methods of preparation, and quality control of thefast-dissolving oral thin films.

Keywords: Oral Film, Patient compliance, first-pass metabolism, hydrophilic polymers.